Assay Development Overview
Our assay development services play a critical role in drug discovery, providing accurate and reproducible data for evaluating potential drug candidates. Assays are essential in identifying therapeutic targets, screening compounds and validating drug efficacy,
toxicity and mechanism of action.
As an integrated biology service provider, we leverage the latest assay platform technologies to support research across small molecules,
TPD and PROTACs,
peptides and ADCs.
Our assays are supported by:
1,000+ in vitro assays covering a diverse range of targets.
600+ in vivo models to support translational and preclinical studies.
State-of-the-art facilities, including AAALAC-accredited animal facilities.
Expert teams of scientists with deep expertise in biochemical assay development, biological assay development and custom assay development.
By integrating cutting-edge screening techniques, such as high-throughput screening (HTS), receptor binding assays and
cell-based assays, we provide comprehensive solutions that accelerate the drug development process and enhance decision-making.
Highlights
Comprehensive Assay Capabilities: Expertise in biochemical, biological and custom assay development, adaptable to diverse research needs.
Advanced Assay Detection Methods: Integrating fluorescence, luminescence, TR-FRET, ELISA, LC/MS, SPR and high-content imaging for superior sensitivity and accuracy.
Why Choose BioDuro for Assay Development?
Proven Expertise in Drug Discovery: With 28 years of experience and over 265 IND-enabling projects supported, we are a trusted partner for global pharmaceutical and biotech companies.
Integrated Approach for Accelerated Development: Our assays align with DMPK, preclinical pharmacology, and translational research, reducing time-to-market.
Global Reach & Scalable Solutions: Seven research sites across the US and China, delivering IP-secure, high-quality assay development at scale.
Our Assay Development Services
Biological Assay Development
We provide biological assay development services to support therapeutic candidate validation, including:
Cell-based assays for evaluating drug efficacy.
Receptor binding assays for assessing drug-target interactions.
Functional assays for signal transduction and target engagement.
Biochemical Assay Development
Enzyme-linked immunosorbent assays (ELISA) for detecting and quantifying specific substances.
Protein interaction studies to evaluate drug effects on biochemical targets.
Screening for biochemical processes, including kinase assays, enzyme activity assays, and metabolite profiling.
Recombinant protein expression and fragment-based screening, enabling precise assays for protein interactions and drug discovery.
Custom Assay Development
We specialize in custom assay development, designing tailored solutions for therapeutic candidate screening, biochemical target evaluation and mechanistic studies. We develop assays for specific molecular interactions, cell-based responses, and pharmacological assessments, ensuring high sensitivity and reproducibility to meet unique research needs.
Assay Development in Drug Discovery
Assays play a fundamental role in drug discovery, enabling researchers to:
Identify and validate drug targets within the drug development pipeline.
Screen tested compounds for potency, selectivity and potential off-target effects.
Assess toxicity, efficacy and pharmacokinetics to support clinical advancement.
These assays provide critical insights into drug candidate optimization, supporting early-stage research and regulatory decision-making.
Why Assay Development is Crucial in Drug Discovery
Ensures Drug Efficacy & Safety: Assays confirm that therapeutic candidates exhibit the desired biological effects.
Enhances Mechanistic Understanding: Allows researchers to identify molecular interactions and biochemical pathways relevant to drug function.
Supports Regulatory Approval: Assay validation is essential for generating robust, reproducible data required for preclinical and clinical regulatory submissions.
Assay Development Process
At BioDuro, our assay development process follows a structured approach:
1. Assay Design & Development – Selecting the appropriate assay format based on research objectives.
2. Assay Optimization & Validation – Ensuring sensitivity, specificity and reproducibility.
3. Screening & Data Analysis – Evaluating tested compounds for target engagement.
4. Final Reporting – Delivering comprehensive insights to guide drug development decisions.
Contact Us
Accelerate your drug development process with our expertise in assay development services.
Contact us today to discuss your project.
Q&A
How do BioDuro’s assays accelerate drug discovery?
We integrate biochemical and biological assay development, high-throughput screening and translational research with our end-to-end CRDMO platform. Our 265+ IND-enabling projects and state-of-the-art assay technologies ensure precise, reproducible data that streamline candidate selection and regulatory submissions.
What types of custom assays can BioDuro develop?
We develop custom assays for biochemical processes, molecular biology applications, target validation and HTS, ensuring flexibility across research needs.
Why is biological assay development important for drug efficacy?
Biological assays play a critical role in drug efficacy studies by measuring cellular responses, validating mechanism of action and ensuring target engagement, confirming that therapeutic candidates perform as intended.
What makes BioDuro’s assay development services unique?
We offer an integrated drug development pipeline, cutting-edge HTS platforms and unmatched expertise in biochemical and biological assay development—providing faster, more precise results to accelerate your drug discovery.
Home
