Fluorescence, absorbance, luminescence, FP, TR-FRET, HTRF, LANCE, Alpha
Filtration based, SPA based and other radiometric assays
LC/MS
SPR
FLIPR
HiBiT
Simple Western, Western-blot, In-Cell Western, ELISA
FACS and CBA multiplex
High content imaging
PBMC, T cell, B cell and NK cell isolation
T cell activation and proliferation assays
Immuno-phenotyping or biomarkers analysis with multi-color FACS, CBA, ELISA, RT-PCR
Cell proliferation, apoptosis, pyroptosis, migration and invasion, cell cycle analysis
Antibody-dependent cell-mediated cytotoxicity (ADCC)
ADC assays
Full suite of assays for in vitro PROTAC evaluation
Target protein degradation
HiBiT cell line generation using CRISPR-Cas9 technology and evaluation of PROTAC compounds in HiBiT cells
Simple Western with better quantification, less variation, higher reproducibility, shorter turnaround time and lower protein consumption
Western-blot, In-Cell Western/In-Cell ELISA, ELISA, FACS, HTRF, etc.
Cell permeability and target engagement
NanoBRET Target Engagement assay
Binding to POI or E3
Live cell and permeable modes
HTRF, SPR, Co-IP, FP, TSA, etc.
Ternary complex formation
NanoBRET PPI assay
Endpoint
Kinetic
SPR, TR-FRET, AlphaLISA, Co-IP, etc.
Ubiquitination assays and proteasomal recruitment assays
6 conventional radioisotopes are permitted: 35S、32P、33P、125I、14C、3H
Integrated platform for compound screening and MOA verification
Integrated compound screening and MOA study services for epigenetic targets including METTL3/14, P300&CBP, G9a&GLP and PRMT5;
Radioligand-binding assay, including GPCR receptor-ligand binding affinity test;
Radioactive kinase assay for kinase inhibitor screen;
Uptake assays by using radio isotope method, such as glucose uptake;
GTPγS binding assays for GPCR agonists screen;
Radioimmunoassay experiment, metabolite identification experiment and other customized detection requirements.
Radioligand binding assay of A2aR (GPCR)
Radioisotope assay for epigenetics targets
Expand from drug pipelines to potential new targets.
Provide high quality data with fast turnaround time.
Integrated compound screening and MOA study.
Pseudo-virus entry assay
Main protease (3CL Mpro) FRET-based biochemical assay
Papain-like protease (PLpro) fluorescence assay
TR-FRET based ACE2/RBD binding assay
SPR based binding assay
EnVision, Enspire, TECAN Spark M10, SpectraMax
FLIPR Penta, Flexstation
MicroBeta 2, ABI 7500
Flow Cytometers
JESS Simple Western System
High Content Imager Operetta CLS
CFX384 RT-PCR
ADDA High Speed – LC/MS
Multidrop Combi Dispenser
Apricot (Apricot Designs)
Agilent Bravo Automated Workstation
Echo Acoustic Liquid Handler (2.5nL-10μL, Labcyte)
Full Range of standard equipment for cellular and molecular biology
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