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DNA-ENCODED LIBRARY (DEL)

Tailored Engine for Small Molecular Drug Discovery Unlock Exponential Possibilities Screening Billions of Small Molecules

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DNA-Encoded Library (DEL) Screening Services

Advanced DNA-encoded library (DEL) small molecule drug discovery screening services

BioDuro and X-Chem have partnered to provide DEL services since August 2022

High quality lead-like/drug-like focused libraries incorporating state-of-the-art DEL design and synthesis

Thorough protein QC and AI-powered comprehensive DEL selection data analysis

Hit structures with embedded SAR information provided to clients who are offered full freedom to operate

Transparent cost structure, no downstream financial obligations

Unmatched track record for DEL-driven hit identification by X-Chem, backed by comprehensive Discovery services (Chemistry, Biology, DMPK, Pharmacology) to rapidly advance clients’ discovery programs

DEL Screening Services Overview
BioDuro is an exclusive strategic partner of X-Chem in China. X-Chem is the leader in small molecule discovery science, providing pharmaceutical and biotech companies a complete, seamless solution for screening, hit validation and lead optimization. As pioneers of DNA-encoded chemical library (DEL) technology, X-Chem has been leading the DNA-encoded library (DEL) field for more than a decade, delivering over 90 programs to the partners and clients, comprising over 1,000 novel, validated hit compounds across more than 30 different target classes.
The BioDuro Advantage
X-Chem’s versatile DEL screening is proven in projects spanning numerous target classes. The robust process has been highly successful against targets considered difficult or even intractable

Protein-protein interactions

Ubiquitin ligases

Epigenetic targets

G protein-coupled receptors

Bacterial enzymes

Services
The platform, libraries and screening strategies are designed to generate compound classes that can address any target and modality

Lead-like compounds

Drug-like compounds

Macrocycles

Peptides

Covalent inhibitors

Protein degraders

Allosteric inhibitors

How does it work
Peptide
Compound Management
PROTAC Drug Discovery
Bioavailability Enhancement
Integrated Drug Discovery
IND Enabling
DNA-Encoded Library
Preclinical MASH Models
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