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• Associate Director of Chemistry

  Advanced - CN | Wuxi-CN | 化学

  主要活动

   Responsibility:

  Lead Group Leaders and Bench scientists to execute chemistry projects well, to build and maintain positive relationship with clients by providing on-time and high-quality delivery and proactive communications.

   

  • Set up the scientific and operational goal and SOP for the projects assigned; manage and coach Group Leaders and bench scientists; manage resources and control the cost effectively.
  • Proactively participate the Business Development activities with self-initiative or under the assignment from the supervisor.
  • Recruit, train and coach key members of the team, maintain positive morale in the team by setting objective, performance management and people management.
  • As a member of the company’s Sr. Management team, play an active and important role in building and maintaining the company culture, the company’s reputation in the industry by participating internal and external communication events.

  要求

  • PhD. in synthetic organic chemistry or medicinal chemistry with more than 8 years of drug discovery and managerial experience (experience in the U.S. or EU preferred)
  • Successful track record in medicinal chemistry with extensive patent and publication records
  • Ability to operate within aggressive timelines
  • Deep understanding of the pharmaceutical R&D process
  • Strategic thinker with the ability to manage a fast-growing business
  • Flexible and innovative problem solver

  提交简历

• Director/Associate Director of Chemistry

  Advanced - CN | Beijing - CN | 化学

  主要活动

  Responsibility:

   

  Lead Group Leaders and Bench scientists to execute chemistry projects well, to build and maintain positive relationship with clients by providing on-time and high-quality delivery and proactive communications.

   

  • Set up the scientific and operational goal and SOP for the projects assigned; manage and coach Group Leaders and bench scientists; manage resources and control the cost effectively.
  • Proactively participate the Business Development activities with self-initiative or under the assignment from the supervisor.
  • Recruit, train and coach key members of the team, maintain positive morale in the team by setting objective, performance management and people management.
  • As a member of the company’s Sr. Management team, play an active and important role in building and maintaining the company culture, the company’s reputation in the industry by participating internal and external communication events.

  要求

  • PhD. in synthetic organic chemistry or medicinal chemistry with more than 8 years of drug discovery and managerial experience (experience in the U.S. or EU preferred)
  • Successful track record in medicinal chemistry with extensive patent and publication records
  • Ability to operate within aggressive timelines
  • Deep understanding of the pharmaceutical R&D process
  • Strategic thinker with the ability to manage a fast-growing business
  • Flexible and innovative problem solver

  提交简历

• Director/Associate Director of Biologics

  Advanced - CN | Beijing - CN | Biologics

  主要活动

  • Act as the leader of BioDuro’s therapeutic antibody discovery and engineering teams with clients, and lead internal antibody programs.
  • Able to give scientific input and act as biologics leader within cross-functional project teams to evaluate, prioritize and set strategy to positively influence project direction and timelines.
  • Accountable for driving, growing and expanding Biologics teams, as well as communicating with clients, maintain and enhance client relationships, and work with BD to build up new clients.

  要求

  • Ph.D. /MD Ph.D. in molecular biology, and cell biology, biochemistry, pharmaceutical sciences, or equivalent.
  • At least 6+ years industry experiences in therapeutic antibody discovery and engineering area, with expertise in immunology, oncology.
  • Experience of hiring, leading and managing in biological teams.
  • Excellent communication skills and can work as a team player
  • Able to effectively collaborate and drive towards scientific goals in a dynamic, cross-functional matrix environment.

   

  提交简历

• Biocore Scientist

  Shanghai - CN

  主要活动

  We’re seeking an experienced Biacore scientist to support the assay development and sample analysis for both small molecule and biologics drug discovery in the biophysics group at BioDuro.

  1. Hands-on scientific expertise and problem-solving skills in Biacore analysis, and co-ordinate with project teams to streamline the sample characterization process.

  2. Performs Biacore instrumentation routine maintenance, and fully document all protocols and results in notebook and compose summary report.

  要求

  1. MS 2+ years of work experience, preferably in industrial settings.
  2. Extensive knowledge and expertise in Biacore technology and SPR applications, and proven hands-on skills in biomolecular interaction analysis or ligand-binding assay (ELISA, e.g.).

  3. Experience with fragment-based screening using SPR or other biophysical methods is highly desirable. Work experience in GLP invironment, as well as practical knowledge in bioanalytical assays is also desirable.

  4. Strong organization and communication skills, and the ability to work in a team environment.

  5. Fluent oral and written English, and strong literature-searching ability.

  提交简历

• Group Leader of Bioanalysis

  Shanghai - CN

  主要活动

  1. Conduct bioanalytical method development using LCMSMS
  2. Conduct bioanalysis work for PK samples and in vitro ADME samples
  3. Perform PK parameter calculation using WinNonlin software and write study report
  4. Communicate with supervisor about study progress and issues
  5. Peer review other scientists’data
  6. Acting as a project leader and ensure project is delivered error-free and in timely fashion

  要求

  1. MS in Analytical chemistry, Pharmaceutical Science or Pharmacology
  2. Working experience of modern LCMSMS is a must
  3. 5 year experience in DMPK study with at least 2 years management experience.

  提交简历

• Group Leader of Bioanalysis

  Shanghai - CN

  主要活动

  1. Conduct bioanalytical method development using LCMSMS
  2. Conduct bioanalysis work for PK samples and in vitro ADME samples
  3. Perform PK parameter calculation using WinNonlin software and write study report
  4. Communicate with supervisor about study progress and issues
  5. Peer review other scientists’data
  6. Acting as a project leader and ensure project is delivered error-free and in timely fashion

  要求

  1. MS in Analytical chemistry, Pharmaceutical Science or Pharmacology
  2. Working experience of modern LCMSMS is a must
  3. 5 year experience in DMPK study with at least 2 years management experience.

  提交简历

• Senior Director/Director/Associate Director, Medicinal Chemistry

  Shanghai - CN

  主要活动

  Responsibility:

  Lead Group Leaders and Bench scientists to execute chemistry projects well, to build and maintain positive relationship with clients by providing on-time and high quality delivery and proactive communications.

  • Set up the scientific and operational goal and SOP for the projects assigned; manage and coach Group Leaders and bench scientists; manage resources and control the cost effectively.
  • Proactively participate the Business Development activities with self-initiative or under the assignment from the supervisor.
  • Recruit, train and coach key members of the team, maintain positive morale in the team by setting objective, performance management and people management.
  • As a member of the company’s Sr. Management team, play an active and important role in building and maintaining the company culture, the company’s reputation in the industry by participating internal and external communication events.

  要求

  • D. in synthetic organic chemistry or medicinal chemistry with more than 10 years of drug discovery and managerial experience (experience in the U.S. or EU preferred)
  • Successful track record in medicinal chemistry with extensive patent and publication records
  • Expertise in drug targets including GPCR, kinase, ion channel and other enzyme targets is desired. Familiarity with structure-based design is a plus
  • Ability to operate within aggressive timelines
  • Deep understanding of the pharmaceutical R&D process
  • Strategic thinker with the ability to manage a fast-growing business
  • Flexible and innovative problem solver

  提交简历

• Senior Group Leader/Associate Director of Discovery Biology

  Discovery Biology | Shanghai - CN

  主要活动

  Division/Department: Discovery Biology

  Line Manager’s Title: Senior Director of Discovery Biology

  Location: Shanghai

  Responsibility:

  • Lead a team of in vitro biology scientists to develop, optimize, validate and execute biochemical and/or cellular assays to support drug discovery projects, including assay development, and running assays for SAR support and compound profiling
  • Ability to supervise a team to meet project timelines and teach directly writing of assay reports and trouble shooting skills

  The individual is expected to have good communication skills, especially be capable of communicating effectively in English both in writing to communicate project progress and sharing data and in verbal communication to discuss project progress, interpret and present data to clients and the other BioDuro project team representatives

  要求

  • A Ph.D degree in Biochemistry, Molecular Biology, Cell Biology or immunology with at least 1-5 years post-doctoral research experience, preferably in drug discovery industry or CRO
  • Solid background and training in his or her own fields of studies and in conducting research using the latest drug discovery technologies and advances in science
  • Preference will be given to candidates with good knowledge and experience in Oncology, Inflammation, Immunology and ImmunoOncology drug discovery areas
  • Supervisory experience is required
  • Good oral and written communication skills in English (proficiency in Chinese preferred)

  提交简历

• Director, Oncology

  Oncology | Shanghai - CN

  主要活动

  The position is a research leader role with proven organizational & management skill. A team of scientists reporting to this leader will be responsible for contract preclinical research/CRO service in cancer pharmacology and immunooncology related projects.

   

  Responsibilities:

  • As a technical leader, work independently or lead a team to execute multiple internal or external projects;
  • Interact with clients on the service introduction, study protocol, update and report preparation etc.
  • Supervise lab scientists and junior staff

  要求

  • PhD in cancer biology, cell biology, immunology or oncology (or comparable), 10+ years of relevant experience with 2+ industry experience
  • Familiar with various in vitro cell-based and in vivo cancer pharmacology studies
  • Responsible and organized
  • Strong communication and interpersonal skills
  • Good verbal and written English
  • Good at troubleshooting and creative problem-solving

  提交简历

• Director: Discovery Biology

  Discovery Biology | Shanghai - CN

  主要活动

  We are seeking a highly experienced and innovative molecular or cell biologist who will join us as Director of Discovery Biology at BioDuro (Shanghai site). The successful candidate will lead a diverse team of biologists and protein scientists, and will be responsible for all in vitro biochemical and cellular assays, in vitro safety pharmacology studies, and production of biological reagents, including effectively developing and managing all related service contracts. The individual will be expected to drive innovation and develop new enabling capabilities within Discovery Biology, and interact closely with other functions including the biophysics, DMPK and in vivo pharmacology teams.  The successful candidate should have excellent written and oral communication skills, strong leadership experience, and the ability to prioritize options, anticipate challenges, and execute on goals in a fast-paced and customer-oriented environment.

  Key responsibilities include but are not limited to the following:

  • Builds and leads a high-performance in vitro biology team, provides effective mentorship and performance management. Ensures delivery on top financial and productivity goals and maintenance of customer satisfaction.
  • Fosters transparent and supportive communications with clients, project teams, and internally with other cross-functional business units and stake-holders. Technical support for BD work with quotations and contract discussions.
  • Manages the design, validation, and execution of all in vitro biochemical and cell-based assays for diverse classes of drug targets and drug modalities, including mechanistic and phenotypic functional assays as well as various cytotoxicity assays. Ultimately responsible for assay quality, data records, timely and authoritative reporting/interpretation of experimental results to clients or project teams.
  • Manages the timely delivery on high quality recombinant protein production and stable cell line generation.
  • Leads the identification and utilization of current and emerging technologies that are critical to expand BioDuro capabilities and fulfill customer needs in cutting-edge drug discoveries.
  • Ensures proper training and full compliance of EHS rules and government regulations for all members of the Discovery Biology department.

  要求

  Education and Work Experience Requirement:

  • Ph.D. in molecular biology, cell biology, biochemistry, enzymology, or a related scientific discipline with 12+ years of work experience, preferably in a Biotech/Pharmaceutical/CRO setting

  Required Experience:

  • Demonstrated deep expertise in various in vitro biochemical and cell-based assays.
  • Broad experience in drug discovery and in supporting SAR studies of diverse classes of drug targets.
  • In-depth knowledge and experience in certain disease areas (e.g. immunology, oncology or metabolic diseases) is highly desirable.
  • Expertise in mechanistic enzymology and protein chemistry, and familiarity with major biophysical and bioanalytical techniques (e.g. SPR, ITC or MS) is highly desirable.
  • A successful track record of managing a relevant business unit at a CRO is a strong plus.

  提交简历

• Assistant Director, Oncology

  Oncology | Shanghai - CN

  主要活动

  The position is a research leader role with proven organizational & management skill. A team of scientists reporting to this leader will be responsible for contract preclinical research/CRO service on cancer pharmacology and immune-oncology related projects.

  Responsibilities:

  • As a technical leader, work independently or lead a team to execute multiple internal or external projects;
  • Interact with clients on the service introduction, study protocol, update and report preparation etc.
  • Supervise lab scientists and junior staff

  要求

  • PhD or MD in cancer biology, cell biology, immunology or oncology (or comparable), 7+ years of relevant experience with 2+ industry experience
  • Familiar with various in vitro cell-based and in vivo cancer pharmacology studies
  • Strong responsibility and organization skill
  • Strong communication and interpersonal skill
  • Good verbal and written English
  • Good at troubleshooting and creative problem-solving

  提交简历

• Senior Scientist of Immunology / Cell Biology

  Biologics | Shanghai - CN

  主要活动

  Exciting opening in a brand new team that will focus on the most recent technology of cell based immunotherapy. The ideal candidate will be trained and working directly with top scientists from an international Pharma, lead and manage his/her own group to conduct research in Cancer Immunotherapy field. The title will be based on the actual experience of candidates.

  要求

  The candidate is expected to meet the following requirements:

  PhD in immunology, neurobiology, cell and molecular biology, biotechnology, biochemistry, genetics or any other relevant areas.

  1. Analytical, detail-oriented, organized, efficient, problem-solver, adaptable, independent but also works well in a cross-functional team
  2. Strong experience in mammalian cell culture, cell transduction/transfection techniques, and analysis
  3. Highly Desired:
  4. Primary human immune cell isolation and culture (T cell, NK cell, etc.)
  5. Experience with cytoxicity assays (ADCC, CDC, etc.) and cytokine release assays
  6. Lentiviral transduction
  7. FACS based analysis
  8. ELISA
  9. English: speaking fluent English, strong in writing and record keeping.

   

  提交简历

• Sr. Scientist of Animal Pharmacology

  Pharmacology | Shanghai - CN

  主要活动

  Exciting opening in a brand new team that will focus on the most recent technology of cell based immunotherapy. The ideal candidate will be trained and working directly with top scientists from an international Pharma, lead and manage his/her own group to conduct research in Cancer Immunotherapy field. The title will be based on the actual experience of candidates.

  要求

  The candidate is expected to meet the following requirements:

  PhD in immunology, neurobiology, cell and molecular biology, biotechnology, biochemistry, genetics or any other relevant areas / experience.

  1. Analytical, detail-oriented, organized, efficient, problem-solver, adaptable, independent but also works well in a cross-functional team
  2. Able to communicate plans and results effectively in English and Mandarin
  3. Strong experience in designing and running animal models to evaluate efficacy of novel cancer therapeutics, animal husbandry / experimentation, and sample size determination for statistical significance

     Highly Desired:

  • Experience with human xenograft cancer models (cell lines. PDX) in immunocompromised mice (ex. NSG mice)
  • Experience with tail vein injection of immune cells into mice
  • Experience with subcutaneous and peritoneal cancer models
  • Experience with in vivo optical imaging technology to follow disease progression and cell trafficking with bioluminescent and fluorescent probes ((Xenogen IVIS, LI-COR, etc.)
  • Experience with chimeric antigen receptor in vivo studies
  • English: speaking fluent English, strong in writing and record keeping.

  提交简历

• 总监/副总监，药物化学

  上海 | 化学

  主要活动

  领导一个组长团队和替补科学家执行化药项目，建立并通过提供及时和高质量的交付和积极主动的沟通与客户保持积极的关系。

  • 设置指定项目的业务目标和SOP;管理和教练组长跟替补科学家;管理资源并有效地控制成本。
  • 积极主动拓展业务领域及配合上级拓展业务。
  • 招聘，培训和训练团队的主要成员。通过设定目标，绩效管理和人员管理维护增强团队士气。
  • 作为公司的高级管理团队中的一员，在建设和维护公司的文化、公司在同行中的名望，通过参与内部和外部沟通活动中发挥积极和重要的作用。

  汇报对象: 高级总监，药物化学

  地点: 上海

  要求

  • 博士，有机合成化学和药物化学专业，8年以上药物研发或管理经验（美国或欧洲优先）
  • 在相关的药物靶标，包括GPCR，激酶，离子通道和其他酶的目标专业领域精通。熟悉基于结构基础设计者优先。
  • 熟悉CRO业务和运营
  • 能在有限的时间节点交付
  • 对制药研发行业有深刻的理解
  • 战略的眼光管理快速增长的业务
  • 灵活和创新的解决问题
  • 在药物化学领域有夯实的经验且有广泛的专利和出版记录

  提交简历

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