我们的圣地亚哥站点是我们的公司总部。该设施是保诺医药产品开发技术的所在地，拥有 9 间 GMP 洁净室。开发和制造业务针对直至 III 期临床试验的项目进行。
Featured capabilites: Tableting, Coating, Hot Melt Extrusion, Spray Dried Dispersion
11011 Torreyana Rd.
Type 1 diabetes, also called Juvenile diabetes, is an auto-immune condition where the pancreas produces little or no insulin. The only known treatment involves insulin administration which manages the symptoms without treating the cause. Methyldopa has been shown to re-program T-cells, which protect the islet cells in the pancreas from destruction. Absorption is limited to 50% in oral doses in the upper gastrointestinal tract. Hence, a gastro-retentive dosage form is required to increase absorption efficiency of methyldopa.
Poster on formulation of a novel gastro-retentive sustained release oral formulation for methyldopa to treat Type I diabetes, presented by Ruchit Trivedi, Ph. D., at AAPS 2016.